Cannabidiol (CBD) is a naturally-occurring constituent of industrial hemp (cannabis sativa) plants. It is the most abundant non-psychoactive cannabinoid found in cannabis and is being scientifically investigated for numerous reasons. Most people have heard of a cannabinoid called THC, which is the ingredient in cannabis that gets users high. Unlike THC, CBD (cannabidiol) is a non-psychoactive cannabinoid and does not cause a high.
CBD it not a drug. CBD helps restore homeostasis (balance) through its effects on our Endocannabinoid System.
What am I buying?
Choose from Organic CBD Pain Topical Creme for Arthritis, Pain, Inflammation with Organic Full Spectrum CBD Oil, High Grade Hemp Extract (50mg/ml) in :
2oz (180mg CBD)
4 oz (360 mg CBD)
8 oz (720mg CBD)
Ingredients: Butyrospermum Parkii (Shea Butter), Heterotheca indloides (Arnica Flowers), Organic 480mg Full Spectrum CBD Oil - High Grade Hemp Extract (50mg/ml), Prunus armeniaca (Apricot Oil), Carthamus tinctorius L (Safflower Oil), Helianthus (Sunflower Oil), Peppermint Oil, Non GMO Vitamin E.
-All natural, raw, with no additives or preservatives
-Made from non-GMO hemp plants grown on select farms in Colorado, USA
-100% Organic; NO herbicides, pesticides, or chemical fertilizers used
-Legal in all 50 states and in over 40 countries
CBD and other cannabinoids are naturally occurring compounds that display potent anti-inflammatory and pain-relieving properties. They can promote the body’s healthy regulation of the central nervous, immune, and endocannabinoid systems.
Your body contains cell receptors known as cannabinoid receptors; Cannabinoids, found in cannabis, are agonists that are able bind to these receptors initiating a physiological response.Together all of these cells make up the larger endocannabinoid system (ECS). If cannabinoid receptors are locks, then agonists – or the cannabinoids found in CBD – are keys. CBD interacts with cells in our bodies that we produce naturally called endocannabinoids. These cells are able to interact due to their similar composition.
The ECS system has been described as the greatest neurotransmitter system in the body and has a hand in just about everything your body does including:
- Autonomic nervous system
- Female reproduction
- Immune system
- Stress response
The endocannabinoid system plays an important role in the immune response of our skin. An improper immune response can result in inflammation and this is why CBD is works as an anti-inflammatory, cell renewal and wound healer for skin conditions. Both CB1 and CB2 receptors have been found throughout the skin.
How do you know how much CBD is in your products?
Our CBD oil is lab-tested as soon as
it is extracted and then again by a third party lab (Steep Hill) in Berkeley,
California, to ensure an accurate amount of CBD. In addition, we test for over
200 pesticides, herbicides, mold, fungi, heavy metals, and mycotoxins. We use
cutting-edge testing and world-class equipment to ensure that our products are
safe and healthy.
Is your CBD a whole plant extract, synthetic, or an isolate?
We would never sacrifice quality by providing a synthetic CBD or CBD isolate blend. We use a whole plant extract that is rich in cannabinoids, terpenes, and other beneficial oils. The Hadassah Medical School at the Hebrew University of Jerusalem sought to compare the effectiveness of a completely purified CBD extract versus a full-spectrum extract of cannabis flowers containing large quantities of CBD. The conclusion of the study was that the whole plant extract, which contained a large percentage of CBD but also contained traces of the other cannabinoids, proved far more effective than CBD-only solutions in alleviating inflammation and pain sensation.
What other cannabinoids are in your CBD oil?
Our full-spectrum CBD oil contains high concentrations of CBD and also other beneficial cannabinoids such as CBC, CBG, CBDA, and CBDV. These beneficial cannabinoids are not psychoactive and are being studied scientifically for a wide variety of health benefits. Cannabinoids work synergistically together with what is known as the entourage effect.
When does the product expire?
Without refrigeration, the product will last for 12 months. Refrigeration is completely optional but will extend the shelf life of the product to 18 months.
What other ingredients are in your CBD oil?
Our CBD oil has only one ingredient, hemp! Our extracts contain 100% organic cold pressed hemp oil and our proprietary full spectrum CBD concentrate. There are no other additives, preservatives, emulsifiers, or flavorings.
Where do you source your hemp from?
Our CBD oil is extracted from organic hemp plants cultivated on licensed farms in Colorado, USA – all nourished with pristine Rocky Mountain water and lots of sunshine. It’s grown the way nature intended and harvested at peak perfection.
Why is NuLeaf Naturals not USDA certified?
The USDA has made the statement that they will not certify any hemp products grown in the United States at this time. We partnered with an industry-leading third-party lab, Steep Hill, to ensure that our CBD oil is 100% organic. Please contact us for current lab results.
Green Extraction Methods
How do you extract the CBD and other cannabinoids from the raw plant material?
We use green extraction methods that utilize CO2, which leaves behind no toxins, heavy metals, or chemicals to degrade the product in any way. CO2 is safe to use in food products and commonly found in carbonated beverages, and our bodies even produce CO2 when we breathe!
What type of CO2 extraction do you use?
We use a combination of both Subcritical and Supercritical extractions. This allows us to perform a “fractional extraction” by first extracting at lower temperatures and pressures to remove the lighter, temperature-sensitive volatile oils, and then subsequently extracting the same material at a higher pressure and temperature to remove the remaining oils. This approach is the best because it allows us to extract a complete range of cannabinoids, terpenes, essential oils, and other beneficial phytochemicals that yield a more potent blend.
Store in a cool dark place; shake well before each use.
Produced by NuLeaf Naturals
*FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE These statements have not been evaluated by the FDA and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program.
How to Use: Apply Liberally to affected area.
Study: Topical CBD Treatment May Reduce Central Nervous System Inflammation
A controlled animal study published in Daru: Journal of Faculty and Pharmacy, Tehran University of Medical Sciences found that topical treatment with 1% purified (i.e. >98%) CBD topical cream may help to reduce damage caused by a disease that results in brain inflammation. This holds relevance for humans with autoimmune diseases that lead to demyelination (damage to the fatty covering around neurons that helps them to transmit signals faster) like multiple sclerosis.
Topical CBD vs. Multiple Sclerosis Experiment
Using healthy mice and mice with experimental autoimmune encephalomyelitis [(EAE)- encephalo= brain, myel= myelin= fatty nerve covering, itis= inflammation] as models for humans with multiple sclerosis, researchers applied either 1% purified CBD cream, inactive cream, or no cream to the skin of the healthy mice, and to the skin of diseased mice once symptoms of EAE began to appear. The mice were observed daily, and 28 days after EAE had been induced, spinal cord and spleen cell samples were taken.
Results of the Study
The researchers found that treatment with CBD cream helped to reduce damage caused by EAE, characterized by:
- reversal of back leg paralysis (i.e. loss of muscle function)
- reduction in indicators of spinal cord damage like demyelination and white blood cell count
- reduction in release of lymphocytes from spleen cells
- reduction in inflammatory signals
The results of this study provide further support for the potential of cannabinoids in reducing damage caused by autoimmune/inflammatory diseases like multiple sclerosis. More uniquely, however, they show that cannabinoids may produce beneficial biological effects even when only applied to the skin, as opposed to typical internal administration (e.g. edibles, vaping, smoking).